Diseases and Conditions

Phenylketonuria (PKU)

Risk factors

Risk factors for inheriting PKU include:

  • Having both parents with a defective gene that causes PKU. Two parents must pass along a copy of the defective gene for their child to develop the condition.
  • Being of certain ethnic descent. The gene defect that causes PKU varies by ethnic groups and it's less common in African-Americans than in other ethnic groups.